Dapcel, Inc. is a research biotechnology company in Cleveland, Ohio. Our gene-design approach, DAPCEL™ RC (Rare Codon) optimization, takes rare codons and the kinetics of translation into account when redesigning a coding sequence, with the aim of producing correctly folded, soluble protein. We use it in our own protein production and offer it as a separate service.
DAPCEL™ Products
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DAPCEL™ Proteins
Recombinant proteins produced with rare-codon-informed optimization, each with purity and endotoxin data and, where assigned, functional activity.
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DAPCEL™ CELL lines
Dapcel, Inc. cell lines are intended for use by researchers investigating the molecular mechanisms of various normal and disease processes.
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DAPCEL™ Antibodies
Dapcel, Inc. antibodies are coming soon.
DAPCEL™ Services
DAPCEL Inc. offers the following Services to boost your Research
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Synthetic gene design and codon usage optimization -
Custom Protein Production and Purification -
Molecular Cloning and Expression -
Testing actual protein expression levels, and solubility -
Bio-activity Test Development and Performance
Customer Reviews
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"The optimization strategies used by DAPCEL allowed us to obtain expression of 270 kDa recombinant protein in E. coli at substantial levels, the result that we could not achieve before. We really appreciated their efforts and highly recommend them."
Drs. L. Ryabova and M. Schepetilnikov, Institut de Biologue Moleculaire des Plantes (IBMP), Strasbourg, FRANCE -
"The optimization approach used by DAPCEL provided us with very high levels of recombinant protein expression - we really appreciated their excellent work and strongly recommend them."
Drs. Chenhui Wang and Xiaoxia Li, Cleveland Clinic, Lerner Research Institute.
News
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DAPCEL Inc Human Umbilical Vein Endothelial Cells (HUVECs) immortalized with GSE56 are now available through Fisher Scientific™
DAPCEL Inc Human Umbilical Vein Endothelial Cells (HUVECs) immortalized with GSE56 are now available through Fisher Scientific™
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DAPCEL Inc enters into licensing agreements with Thermo Fisher Scientific and Daresbury Proteins Ltd
DAPCEL Inc enters into licensing agreements with Thermo Fisher Scientific and Daresbury Proteins Ltd regarding its patented technology for enhanced recombinant protein expression in mammalian cells.