Dapcel, Inc. is a research biotechnology company focused on the development of strategies for optimization of enhanced protein production. To this end Dapcel, Inc. utilizes its unique Two-Layered DAPCEL™ RC (Rare Codon) Gene Optimization approach for gene redesign. The approach takes into account the importance of rare codons and overall kinetics of protein translation guided by synonymous codon usage for protein folding, to favor high yields of correctly folded, soluble protein.
The approach is designed to be host-agnostic. Its documented published results to date are in E. coli, including large and historically difficult proteins; for other hosts we state the expected improvement and its boundaries for your specific construct, rather than making a blanket “any host” guarantee.
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DAPCEL™ Products
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DAPCEL™ Proteins
Recombinant proteins produced with rare-codon-informed optimization, each with purity and endotoxin data and, where assigned, functional activity.
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DAPCEL™ CELL lines
Dapcel, Inc. cell lines are intended for use by researchers investigating the molecular mechanisms of various normal and disease processes.
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DAPCEL™ Antibodies
Dapcel, Inc. antibodies are coming soon.
DAPCEL™ Services
DAPCEL Inc. offers the following Services to boost your Research
Customer Reviews
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"The optimization strategies used by DAPCEL allowed us to obtain expression of 270 kDa recombinant protein in E. coli at substantial levels, the result that we could not achieve before. We really appreciated their efforts and highly recommend them."
Drs. L. Ryabova and M. Schepetilnikov, Institut de Biologue Moleculaire des Plantes (IBMP), Strasbourg, FRANCE
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"The optimization approach used by DAPCEL provided us with very high levels of recombinant protein expression - we really appreciated their excellent work and strongly recommend them."
Drs. Chenhui Wang and Xiaoxia Li, Cleveland Clinic, Lerner Research Institute.
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